suggesting that the activators are not essential for normal mammalian cell proliferation. We propose that under normal conditions E2Fs do not substantially contribute to the proliferative ...

The basic mechanisms that control neural development are intricate, and as research from St. Jude Children's Research ...

The fundamental processes that govern neural development are complex and, as findings by scientists at St. Jude Children's ...

This is a family of conserved non-receptor serine/threonine kinases that integrate a number of signaling pathways essential for normal cell proliferation, survival and motility. Group 1 PAKs also ...

Our lab studies the mechanism of eukaryotic chromosome replication. Chromosomes are the carriers of the genetic and epigenetic information and faithful chromosome replication is of fundamental ...

Scientists at St. Jude Children’s Research Hospital found that, in neural development, the same set of proteins involved in cellular self-renewal can also facilitate differentiation with the right ...

it could be that you could shut down just one branch of its activities that is more important for tumor proliferation while minimally disrupting normal cell function," said Taatjes. The result ...

NEW YORK – PeproMene Bio will expand the ongoing Phase I PMB-102 study of its BAFF-R-targeted CAR T-cell therapy PMB-CT01 after showing initial efficacy in seven lymphoma patients, the firm said ...

"An exciting finding was when we tried to treat the obese mice with colon inflammation by lowering their inflammation, it actually stopped the ERK pathway in the liver from activating," explains Imai.

Researchers at the Tohoku University Graduate School of Medicine have uncovered a key primary step in the hepatic ERK pathway ...