This localized Notch activity is probably mediated by regulation of Notch ligand expression — as Delta-like proteins 1 and 4 (DLL1 and DLL4) are expressed only at the base of the trabeculae ...

Expression levels of the Notch1, Notch4 ... Proc Natl Acad Sci U S A 2008; 105(31): 10901–10906. 11. ZhuGe Q, Zhong M, Zheng W, et al. Notch-1 signalling is activated in brain arteriovenous ...

Using a murine model and genetically modified human cell lines, we confirmed that miR-30a influences NOTCH expression in a MYC-dependent fashion. In turn, through genetic modulation, we ...