A cell signaling mechanism of fundamental importance to animal development is the Notch pathway (Figure 1). It may be safely said that Notch signaling is required, in some reasonably direct fashion, ...

NOTCH signaling plays a crucial role in tumorigenesis and therapeutic resistance, with its activation linked to drug resistance in various cancers. The NOTCH family includes four receptors (NOTCH1 ...

In this long-term work, the researchers demonstrated that the NOTCH signaling pathway, conserved throughout the evolution of all multicellular organisms, plays an essential role in the ...

NOTCH signaling plays a crucial role in tumorigenesis and therapeutic resistance, with its activation linked to drug resistance in various cancers. The NOTCH family includes four receptors (NOTCH1 ...