More information: Dave Maurice De Sousa et al, Early Notch signals from fibroblastic reticular cells program effector CD8+ T cell differentiation, Journal of Experimental Medicine (2025). DOI: 10. ...

One broad category is “inhibitory” signaling, whereby Notch prevents a cell from adopting a particular cell fate ... Ueberschär M, Wang W, Zhang C, Kondo S, Aoki T, Schedl P, Lai EC*, Wen J* and Dai Q ...

NOTCH induces MYC, connecting two signaling programs that enhance ... of gain and loss of miR-30a in diffuse large B-cell lymphoma (DLBCL) and T-acute lymphoblastic leukemia (T-ALL) cells ...

Tsakonas, professor of cell biology, emeritus, in the Blavatnik Institute at Harvard Medical School, has received a ...