A new study suggests genetic changes allow horses to produce more energy, while minimizing the toll the energy takes on cells.

In the current study, researchers focused on the gene KEAP1 and the KEAP1-NRF2 pathway, which regulates antioxidant responses and mitochondrial energy production. In birds, this pathway evolved to ...

This particular PLP is structured to alter the interaction between Nrf2 and another protein called Keap1. The proteins' interaction, or pathway, is a well-known target for treating many conditions ...

Scientists have found that the key defense mechanism is the nuclear factor erythroid 2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1) signaling pathway. Nrf2 activates ...

Chemoresistance is the most significant challenge affecting the clinical efficacy of the treatment of patients with gastric cancer (GC). Here we reported that transmembrane protein 160 (TMEM160) ...