The modification state helps determine whether the nucleosome is an appropriate substrate for a remodeler complex (Saha et al., 2006), as discussed later in this article. Chromatin structure is ...

A second epigenetic mechanism implicated in learning and memory involves modification of histones, the proteins that DNA wraps around for organization and packaging within the nucleus 3,7. The basic ...

Starting with the structure of the nucleosome and continuing with histone modifications, chromatin-remodeling complexes, silencing factors and more, a detailed and dynamic picture of chromosomal ...