Starting with the structure of the nucleosome and continuing with histone modifications, chromatin-remodeling complexes, silencing factors and more, a detailed and dynamic picture of chromosomal ...

Instead, the chromatin remodeling complex SWR1 catalyzes an ATP-dependent exchange of H2A in the nucleosome for H2A.Z (Wu et al., 2005). Histone sequences are highly conserved. The diagram in ...

The research, led by scientists at The Institute of Cancer Research, London, revealed that targeting the nucleosome-remodeling factor (NURF) complex, particularly by inhibiting a specific cancer ...