Starting with the structure of the nucleosome and continuing with histone modifications, chromatin-remodeling complexes, silencing factors and more, a detailed and dynamic picture of chromosomal ...

One particular type of epigenetic modification concerns histones ... ‘SNAP-ChIP verified’ antibodies for histone PTMs by using defined spike-in nucleosome controls to validate specificity ...

A second epigenetic mechanism implicated in learning and memory involves modification of histones, the proteins that DNA wraps around for organization and packaging within the nucleus 3,7. The basic ...

The DNA (red) is wound around two sets of core histone proteins (green) to form a kind of bead on a string. The H1 histone protein clamps the DNA into place where it enters and exits a bead.

Simple at first glance, this epigenetic regulation is much more complex, as there are many different modifications that can either be attached directly to our DNA or to so-called histone proteins.