DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

There are 11 nucleotide positions at which the original sequence contains the incorrect nucleotide (all sequences here refer to that of the CRS mtDNA L-strand), one of which involves the CC ...

One reason cancer is so difficult to eradicate is its metabolic flexibility, she said. Her findings suggest that the salvage pathway could be an access route for cancer cells to get their nucleotide ...

This study provides compelling evidence that kinesin's stepping mechanism is governed by strain-induced conformational changes in its nucleotide-binding pockets. Using pre-steady state kinetics and ...