A particularly surprising discovery was that chromatin accessibility and gene expression can be independently regulated during early embryonic development. Until now, it was often assumed that open ...

This modification results in a loosening of the coil. Histone modification can open chromatin, thus permitting selective binding of transcription factors that, in turn, recruit RNA polymerase II ...

UChicago study combines genetic data with computational models to pinpoint likely genetic variations which cause asthma onset ...

For instance, histone acetylation reduces the positive charge of the histone proteins, thereby reducing their affinity for DNA and causing the chromatin to open (Figure 2). This in turn permits ...

April 3, 2025) Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this ...

EDINBURGH, Scotland, April 14, 2025 /PRNewswire/ -- Chromatin Bioscience, a leader in the design of synthetic promoters and gene control systems, is pleased to announce a collaboration agreement with ...

EDINBURGH, Scotland, April 14, 2025 /PRNewswire/ -- Chromatin Bioscience, a leader in the design of synthetic promoters and gene control systems, is pleased to announce a collaboration agreement ...

Chromatin Bioscience, a leader in the design of synthetic promoters and gene control systems, announced a collaboration agreement with Astellas Pharma, a global life sciences company. Under the ...