suggesting orexin’s role in prioritizing exercise. However, blocking orexin signaling did not change the behavior of mice when they were offered only the running wheel and not the milkshake: Both ...

Of those choices, one was an exercise wheel and another was either ... Professor Burdakov says: 'This means that the primary ...

How the combination of HIIT with intermittent fasting or a low-calorie diet improves metabolic health among postmenopausal ...

Selected research acheivements: Tesmer AL, Li X, Bracey E, Schmandt C, Polania R, Peleg-Raibstein D, Burdakov D (2024) Orexin neurons mediate temptation-resistant voluntary exercise. Nature ...

When you’re awake, those neurons send out orexins. The orexins then bind to certain orexin receptors on other neurons. When that happens, the amount of activity of those neurons goes up.