Few mouse tumor models, however, are conducted in the orthotopic site. Even if orthotopic implantation studies are done, the therapy is typically initiated in mice harboring a small tumor volume ...

therapy reduces intracranial tumor burden, prolongs survival in orthotopic IDH-WT GBM mouse model, and suppresses MGMT." Researchers from Brown University, led by first author Lanlan Zhou and ...

today announced positive data from orthotopic pancreatic cancer models demonstrating that subcutaneously administered SIL204 effectively reduces both primary tumor growth and metastatic spread.