Few mouse tumor models, however, are conducted in the orthotopic site. Even if orthotopic implantation studies are done, the therapy is typically initiated in mice harboring a small tumor volume ...

Sunshine Biopharma Inc. has completed additional studies on orthotopic human tumor models in mice confirming its K1.1 mRNA lipid nanoparticle (K1.1-mRNA-LNP) product as a novel therapeutic agent for ...

Following encapsulation in two specifically designed Lipid Nanoparticles, the resulting K1.1c-mRNA-LNP and K1.1d-mRNA-LNP were efficiently delivered to orthotopic engrafted HCC tumors in mice in a ...

A Canadian pharmaceutical company is turning heads so far during Wednesday’s premarket hours after the company announced that it has completed additional studies on orthotopic human tumor models in ...

This strategy integrates systemic administration to target metastatic progression with intratumoral administration to focus on primary tumors ... clinically relevant orthotopic models of ...