JNK/p38 MAPK的协同调控 磷酸化抗体检测发现WD同步激活JNK和p38 MAPK,双通路抑制剂联用比单抑制剂更显著降低凋亡率(p<0.01)。图4A展示通路蛋白表达变化,但被质疑与图3A存在图像重叠。 体内外实验验证治疗潜力 小鼠异种移植模型中,WD组肿瘤体积减少70% ...
One target for such inhibition, the p38 mitogen-activated protein kinase (MAPK) signaling cascade, has a role in inflammation by mediating the cellular response to stress, pathogens, and cytokines.
The anti-melanogenesis effect of ligustroside derived from Ligustrum japonicum and its underlying mechanisms are explored.
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