肾癌（Renal cancer，RC）是致死率最高的泌尿系统恶性肿瘤，30% 的患者确诊时已处于晚期。超过 50% 的肾癌患者没有明显症状，多为偶然发现。目前，肾癌检测主要依靠影像学检查，但对小尺寸肿瘤的检测灵敏度欠佳。因此，亟需一种灵敏且可靠的诊断工具，推动肾癌标准化早期检测。在本研究中，研究人员对肾癌组织和尿液样本进行全基因组甲基化测序，以探寻肾癌 DNA 甲基化标记物。研究人员利用 93 例 ...

On February 18, 2025, Gilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications ...

PCR-Machines are based on Polymerase Chain Reaction (PCR) and produce copies of genes exponentially. The PCR cycling reactions are carried out in an automated thermocycler, which is capable of ...

在此背景下，伊朗医科大学（Iran University of Medical Sciences）细胞与分子研究中心以及医学系生物技术部门的研究人员挺身而出，开展了一项极具意义的研究。他们致力于开发一种多重实时聚合酶链式反应（Polymerase Chain Reaction，PCR）检测方法，以快速、准确地识别 15 种高危和可能高危的 HPV 基因型。研究成果发表在《Infectious ...

Most genotyping is performed by polymerase chain reaction (PCR) with defined oligonucleotide primers. In order to analyze the length of the PCR products by electrophoresis and a laser detection ...

Bio-Rad’s assays use real-time polymerase chain reaction technology to amplify and detect specific DNA sequences of target ...

Ultra-rapid digital droplet PCR can measure the levels of tumor cells in a tissue sample during surgery in about 15 minutes.

NOAA Fisheries Office of Law Enforcement said a new genetics analysis device helped detect 27 tons of trafficked seafood ...

University of Illinois at Urbana-Champaign researchers have developed a CRISPR-based diagnostic tool capable of detecting ...

Recent outbreaks of highly pathogenic avian influenza (also known as bird flu) have created a need for rapid and sensitive ...

Ensitrelvir PEP was safe and effective for COVID-19 prevention among household contacts when administered after the onset of symptoms in an index patient.