You have full access to this article via your institution. To demonstrate the power of PCR–mediated recombination and provide an example of the general utility of the method, we constructed ...

A poor man's approach to genotyping for research and high-throughput diagnostics. Genotyping with microsatellite markers was first described by Litt and Luty, and is now a widely used method in ...

Originally, the method used radioactive isotope markers to detect targeted genetic materials ... while when used ‘conventionally’, results are only visible at the end of the reaction. PCR is one of ...

A new thermocycler technology helps scientists optimize reactions with six different settable temperature zones for better ...

Digital PCR to simultaneously detect SMN1 gene defects and the number of SMN2 copies to diagnose SMA matches standard methods ...

When the first thermal cyclers for the polymerase chain reaction came out in the 1980s ... largely shutting STEM classes and biohackers out of the PCR market. That may be about to change, though ...

At this stage, researchers changed the reaction temperature by manually moving tubes between water baths set at different temperatures, a procedure that was time consuming and not sustainable long ...

PCR genetic analysis has been in the spotlight since COVID-19, but light is now further facilitating PCR-free methods. Osaka Metropolitan University scientists have developed a light-induced DNA ...