Melanoma is the deadliest form of skin cancer, and cases are rising. Since 2000, diagnoses in the U.S. have increased from 18 to 24 per 100,000 people. Scientists attribute this rise partly to ...

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review ...

Additionally, its interaction with signaling pathways such as PI3K, MAPK, and p53 suggests that targeting ELF4 may pave the way for precision medicine and targeted therapies. Despite significant ...

Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy ...

Blocking MAPK activity abolished the effects of oestradiol ... the activation of ERs by oestradiol increases PI3K activity, which enhances presynaptic glutamate release. This in turn increases ...