The phosphoinositide 3-kinase (PI3K) pathway is a crucial signal transduction system linking the activation of receptor tyrosine kinases (RTKs), G protein-coupled receptors (GPCRs) and oncogenes ...

Control of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P 3) signals in cell survival ... advances in therapeutics targeting the PI3K–Akt pathway, it is likely that targeting this ...

Exposure to air pollution–derived ultrafine particles alters gene transcription by epigenetic mechanisms, a new study shows.

A new study from the University of Eastern Finland shows that exposure to ultrafine particles (UFP) from traffic can ...

Exposure to air pollution derived ultrafine particles alters gene transcription by epigenetic mechanisms, a new study shows. The changes affected, ...

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Anaplastic thyroid cancer (ATC), a rare yet highly aggressive malignancy, continues to represent a major clinical challenge.