Poor oral health is associated with more pain presentations, including migraine, abdominal, and body pain in women.

Na V 1.9 is a voltage-gated sodium channel selectively expressed in peripheral sensory neurones that plays a key role in pain signalling. Mutations in Na V 1.9 are associated with both severe pain and ...

Agents that target NaV1.8, a voltage-gated sodium channel, are showing promise. The FDA approved one of them, Journavx ...

Validated drug discovery assay overcomes previous challenges in targeting NaV1.9 ion channels for chronic pain signalling Completes unique suite of rapid, scalable pain-related sodium channel assays ...

Validated drug discovery assay overcomes previous challenges in targeting NaV1.9 ion channels for chronic pain signalling Completes unique suite of rapid, scalable pain-related sodium channel ...

The authors wrote, "We hypothesise that these (oral) metabolites and/or bacteria trigger heightened pain signalling and defects in pain mechanisms, contributing to the pathogenesis of idiopathic ...

Completes unique suite of rapid, scalable pain-related sodium channel assays ... sensory neurones that plays a key role in pain signalling. Mutations in Na V 1.9 are associated with both severe ...