“There’s great interest and need for drugs with selective D1/D5 dopamine receptor partial agonist activity as a path to minimize the common side effects of current dopamine agonist ...

L-838,417 is a partial agonist at α2, α3 and α5 subunits and an antagonist at α1 subunits. In rats, this compound produced anti-hyperalgesia in inflammatory and neuropathic pain models.

Considering the bioequivalence study of Brexpiprazole Tablets 0.25mg /0.5 mg/1mg/2mg/3mg/4mg, the Subject Expert Committee ...