As Fleming first foresaw, the wartime need for an antibacterial was great, but resources were tight and penicillin still very experimental. Florey had connections at the Rockefeller Foundation in ...

With hundreds of antibacterial molecules ... Suggested target; ESBL: Extended-spectrum β-lactamase; MRSA: Methicillin-resistant Staphylococcus aureus; PBP: Penicillin-binding protein; PTC ...

the antibiotic continues to work,” said VP James Graham. Traditionally, antibiotics have come from natural sources, for instance penicillin, or are modified to achieve broad-spectrum activity.

Drug – Tetracycline: Tetracyclines were first discovered 50 years ago and were found to have broad spectrum antibacterial activity ... compared with vancomycin 1 g intravenously every 12 hours ...

Our thoughtless antibiotic use has encouraged resistance, McKenna says. In part, this is due to the fact that penicillin was sold over the counter until the 1950s; and in much of developing world ...