In Alzheimer's, Parkinson's, and type 2 diabetes, harmful protein aggregates and deposits, known as amyloid plaques, develop.

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Scientists even managed to visualize self-assembly of peptides at unprecedented molecular resolution. They used frequency modulated atomic force microscopy to reveal the molecular architecture of a ...

The molecules contain peptides and a lipid segment, which drives the molecular self-assembly when placed in water. In the new study, the team replaced the lipid tail with a miniature molecular ...

Garner, R., Schafer, D. J., Watkins, W. B., and Young, G. T., Peptides, Proc. Ninth Europ. Peptide Symp., Orsay (edit. by Bricas, E.), 145 (North-Holland, Amsterdam ...

More information: Winssinger, Nicolas, Self-assembled proteomimetic (SAP) with antibody-like binding from short PNA–peptide conjugates, Proceedings of the National Academy of Sciences (2025).

A team at the Technical University of Munich has developed synthetic macrocyclic peptides that inhibit harmful protein aggregation linked to Park ...

Molecular self-assembly has been exploited in Nature to develop the complex higher macromolecular structures of both the genome and proteome. Mohamed’s research interests focus on understanding the ...