A Rac GTPase–regulated multiprotein NADPH oxidase is critical for the formation of reactive oxygen species (ROS) in phagocytic leukocytes and other nonphagocytic cells. NADPH oxidase reduces ...
Phagocytes may engulf both apoptotic and viable cells via calreticulin on the surface of the target cell, through its interaction with the phagocyte receptor, LRP. In reality, however, only ...
A single phagocyte typically ingests an entire apoptotic corpse, essentially doubling its content. Because phagocytes often ingest multiple targets in succession, we propose the existence of ...
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