Here we describe a mouse Fc receptor, designated Fcα/μR, and its human homolog, that bind both IgM and IgA with intermediate or high affinity. Fcα/μR is constitutively expressed on the ...

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

X-ray and nuclear magnetic resonance studies have also revealed conformational changes that occur on IgE binding to its high-affinity receptor FcεRI (high-affinity Fc receptor for IgE ...

This was because these antibodies—which target the immune-suppressing PD-L1 molecule and the growth-promoting epidermal growth factor receptor ... Fc tail, we specifically augmented phagocytosis ...

Tissue-resident macrophages posses a wide variety of phagocytic receptors that vary across tissue, and that engage in the recognition and following phagocytosis of the apoptotic cargo (A). We aim to ...