Plasma cell leukemia (PCL) is a rare disease that may present de novoor secondary to plasma cell myeloma. Advanced disease and extramedullary involvement are common clinical features at presentation.

Long-lived plasma cells, which produce autoantibodies in diseases such as systemic lupus erythematosus (SLE), are an as yet unexplored therapeutic target in such antibody-mediated disorders.

Plasma cells with characteristics of long-lived cells, and factors necessary for long term survival, are present in the salivary glands of patients with primary Sjögren's syndrome (pSS), report ...