Although early indications suggest that these new therapeutics are well tolerated, stimulation of c-Mpl may potentiate platelet activation and trigger thrombosis, a particular concern for older ...

It is characterized by the formation of blood clots (thrombosis) and thrombocytopenia, or low platelet counts. Thrombosis: Blood clots, or clumps, can occur in arteries or veins. They have the ...

Dr. Woulfe's research interests focus primarily on the intracellular signaling mechanisms of platelet activation and how signaling in platelets contributes to thrombosis in vivo. Agonists that extend ...

Platelets are cells that help your blood clot. Without enough platelets, your body may have difficulty stopping bleeding, whether it's from a cut or inside the body. You might have a low platelet ...

CHICAGO — Three months of dual antiplatelet therapy after PCI may safely balance thrombosis and bleeding risk in both patients with low and high bleeding risk, compared with 1 and 12 months of ...