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综述:AKT1 结构与激活机制研究:为靶向治疗开辟新路径
为解决 AKT1 相关药物研发难题,研究人员探究其结构与激活机制,为靶向治疗提供依据。 在细胞的微观世界里,信号传导如同精密的交响乐,掌控着细胞的生死、增殖与代谢。AKT1,作为丝氨酸 / 苏氨酸激酶(serine/threonine kinase)家族的关键成员,在这场 ...
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