The main raw materials used for the production of polyurethanes are polyols, isocyanates and propylene oxide. The first of these is the subject of the latest Rapra Handbook: Chemistry and Technology ...

Glycation of tissue proteins and other macromolecules and excess production of polyol compounds from glucose are among the mechanisms thought to produce tissue damage from chronic hyperglycemia.

These dual-action compounds represent a potential advancement ... playing a key role in the polyol pathway associated with diabetic complications. Polyol Pathway: A metabolic pathway that converts ...