Post-translational modifications are as, or even more, important than transcriptional regulation to finely tune circadian rhythms. Oscillations in period (PER) and cryptochrome (CRY) protein ...

This is achieved by specialized tRNA modification enzymes acting alone or as part of complex pathways. These post-transcriptional modifications provide structural integrity to the tRNA molecule and ...

and functional basis for macromolecules involved in post-translational protein modification by ubiquitin and ubiquitin-like proteins such as SUMO, and pathways that contribute to co- and ...