b Patients taking 25-50 mg once daily should take one supplemental pregabalin dose of 50 or 75 mg after hemodialysis. c Patients taking 75 mg once daily should take one supplemental pregabalin ...

Obermann and colleagues have recently reported that pregabalin, a new drug that reduces release of excitatory neurotransmitters, shows promise as a treatment for TN. Their prospective, open-label ...

Pregabalin binds with high affinity to the ... Peak plasma concentration: 1.5 hours (capsules). Oral bioavailability: ≥90%. Steady state: achieved within 24–48 hours.

Conversion from Lyrica capsules, oral soln: see full labeling. For all: renal impairment (CrCl 30–60mL/min): reduce dose (see full labeling); (CrCl <30mL/min or hemodialysis): dose with Lyrica.