Its exact mechanism of action is unknown. Pregabalin is rapidly absorbed and exhibits linear pharmacokinetics after oral administration. The lack of hepatic metabolism and lack of interaction with ...

Obermann and colleagues have recently reported that pregabalin, a new drug that reduces release of excitatory neurotransmitters, shows promise as a treatment for TN. Their prospective, open-label ...

As pregabalin and gabapentin have a similar mechanism of action, it is not expected that pregabalin would benefit a patient when used concomitantly with gabapentin; however, these drugs could be ...

Pregabalin binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues. Although the mechanism of action of ...

Pregabalin 82.5mg, 165mg, 330mg; ext-rel tabs. Pregabalin binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.