There are trillions of microbes in the gastrointestinal tract, and we are starting to learn more about the exact mechanisms ...

Hepatic synthesis of bile acids is the primary pathway for cholesterol catabolism. The cholesterol 7α-hydroxylase enzyme (encoded by CYP7A1) represents the rate-limiting step of the multi ...

Bacteria naturally present in the human intestine (known as the gut microbiota) can transform cholesterol-derived bile acids ...

Scientists at Weill Cornell Medicine have uncovered a surprising new role for gut bacteria: producing bile acids that can ...

Primary bile acid malabsorption (BAM) accounts for ∼30% of functional chronic diarrhea cases. Julian Walters and colleagues now report that reduced feedback inhibition of hepatic bile acid ...

Nicholas Collins, assistant professor of immunology in medicine, both at Weill Cornell Medicine, are co-senior authors of the study. Primary bile acids are produced by the liver and released into the ...

Guo's lab, are the co-first authors of the study. Primary bile acids are produced by the liver and released into the gut, where diverse groups of bacteria work together to modify their chemical ...

Munich news, health insurance, technology, jobs and other topics for expatriates. The Eye Newspapers covers daily news and offers services for foreigners.

is a chemically modified bile acid that has already shown promising results in the treatment of liver diseases such as primary sclerosing cholangitis (PSC) and is being tested in clinical studies.