PCR genetic analysis has been in the spotlight since COVID-19, but light is now further facilitating PCR-free methods. Osaka ...

The Human Genome Project is expected to yield thousands of single nucleotide polymorphisms (SNPs), which can be used to identify polygenic contributors to disease and ultimately to design ...

suggesting that nucleation can occur at internal positions in probe oligonucleotides. The general similarity in hybridization pattern obtained with arrays containing oligonucleotides tethered by ...

All steps of ISH – from pre-hybridization to additions of probes, hybridization, stringency washes and antibody-mediated chromogenic or fluorescent reaction – are carried out by the robotic system.

Light accelerates DNA hybridization using gold nanoparticles and polystyrene microparticles as probes for PCR-free DNA detection.

In contrast to other in situ hybridization (ISH) methods, this technique uses fluorescently labeled probes to detect specific DNA sequences. Image Credit: Anamaria Mejia/Shutterstock.com FISH is a ...

These probes are short, known DNA sequences designed to hybridize, or bind, with complementary sequences in the target DNA. This process, known as DNA hybridization, allows the matching strands to ...

The fluorescence in situ hybridization (FISH) technique works by detecting fluorescent signals generated when probe molecules bind to specific genetic sequences in bacteria. This innovative FISH ...