The initial report of a patient with visceral scleroderma without skin involvement was published in 1954, [1] and in 1962, the term "progressive systemic sclerosis sine scleroderma" was coined.

Interstitial lung disease associated with diffuse systemic sclerosis. Management ... as treatments for severe, rapidly progressive ILD in the setting of diffuse SSc. There is currently no proven ...

Because it is rare (the incidence rate for the systemic form is estimated to be 19 new cases per year per 1 million adults), many nurses and physicians have only read about scleroderma.

So, what do the symptoms look like? Systemic scleroderma, also known simply as scleroderma, is a chronic connective tissue ...

Professor Christopher Denton discusses key aspects of the 2024 British Society for Rheumatology guideline on managing systemic sclerosis.