Adhesion G protein-coupled receptors (GPCRs) are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for ...

与此同时，研究人员还利用522个蛋白质结构域的信息来推断出相似的蛋白质，这是因为突变通常会对结构或功能相关的蛋白质产生类似的影响，通过分析一组不同的蛋白质结构域，研究人员发现了突变影响蛋白质稳定性的模式，而这些模式在相关蛋白质中或许是一致的。研究者Ben ...

Adhesion G protein-coupled receptors are a large class of membrane proteins that detect chemical and mechanical stimuli in the body. The GAIN domain ...

Scientists at the Faculty of Medicine have now developed an innovative numbering system for the GAIN domain, a protein domain ...

Scientists have now developed an innovative numbering system for the GAIN domain, a protein domain common to all adhesion GPCRs. It should help to better understand the role of this protein domain ...

Researchers have developed a standardized numbering system for adhesion GPCRs, improving knowledge transfer and disease analysis. This AI-driven system, based on 14,000 modelled structures, ...

Disclaimer: AlphaGalileo is not responsible for the accuracy of content posted to AlphaGalileo by contributing institutions or for the use of any information through the AlphaGalileo system.

The aptly named "Human Domainome 1" library computed 563,534 mutant variants across 522 protein domains, representing a more than five-fold increase in scientific knowledge. The study further ...

Adhesion GPCRs are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for therapies.