Periplasmic expression with cytometric screening (PECS) is a powerful and rapid “display-less” technology for isolating ligand-binding proteins from diverse libraries. Escherichia coli ...

You have full access to this article via your institution. Although a considerable fraction of recalcitrant proteins will still need customized production, our findings show that it will be ...

A new study from Oregon Health & Science University has uncovered how small molecules within bacteria interact with proteins, ...

These interactions control important processes such as cell growth, division and gene expression ... Our work in E. coli shows that small molecules interact dynamically with many proteins inside ...