Additionally, each protein contains a wide range of functional groups (groups of atoms attached to the amino acids that participate in specific chemical reactions) that may affect its final shape.

Ionic contacts between protein functional groups and DNA are indicated by arrows, hydrophobic interactions are indicated by perpendicular lines, and hydrogen bonds are indicated by green dashed lines.

Array Bridge is testing promising drug candidates that can effectively bind and even degrade target proteins, but not via ...

As described in the paper, LLNL researchers developed a novel model to better capture the complexity of protein-membrane interactions. Their approach is based on dynamic density functional theory ...

suggesting a completely new functional role and mechanism of action for this plasma protein group. This research proposes a completely new mechanism of action, cell plasma membrane receptor ...