Subsequently, a reactivity function forms a covalent bond ... tool for the isolation of staurosporine-binding kinases from complex protein mixtures. The specificity of the assay is demonstrated ...

Mutations in kinases and phosphatases alter ... The ability of the clock to function when circadian transcriptional regulation of PER proteins is removed indicates the importance of post ...

substrate and inhibitor interactions of tyrosine kinases, and the physical basis for regulation of protein interactions by phosphorylation to gain molecular-level understanding of cellular function.

The scientists discovered that a total of 159 different protein kinases—around a third of ... In addition, it was shown that ...