Mutations in kinases and phosphatases alter ... The ability of the clock to function when circadian transcriptional regulation of PER proteins is removed indicates the importance of post ...

Cyclin-dependent kinases (CDKs) are protein kinases involved in critical ... on the basis of similarities in sequence and function as described below. This nomenclature will facilitate the ...

Mapping the human E3 target protein landscape can help us understand their function and eventually target ... approved therapeutic agents that target kinases, while only a handful of drugs target ...