临床工作中的惯性思维是耐药菌肯定要联合用药，但联合治疗往往是单药治疗效果不佳时的被动选择，感染部位、病情严重程度、耐药菌的种类、耐药机制、耐药谱、耐药水平、联合的药物品种和剂量以及辅助支持治疗手段都是影响联合治疗的因素。

研究结论和讨论部分指出，相同铜绿假单胞菌克隆能形成混合生物膜，可能与它们相似的进化适应过程有关；不同克隆不能形成混合生物膜，这背后的机制可能涉及其他遗传因素，有待进一步探索。此外，研究还发现运动性对生物膜形成的影响并非如以往认知的那样绝对，其他因素如碳源、细胞外 DNA ...

Researchers at the University of Oklahoma have made a discovery that could potentially revolutionize treatments for ...

Owlstone Medical ("Owlstone"), the global leader in Breath Biopsy ® for applications in early disease detection and precision ...

Researchers have made a breakthrough discovery that could potentially revolutionize treatments for antibiotic-resistant infections, cancer and other challenging gram-negative pathogens without relying ...

本期推荐：研究人员针对传统化学合成银纳米颗粒(AgNPs)的高成本与环境污染问题，创新性地利用Pseudomonas aeruginosa-C1M角质酶实现AgNPs的绿色合成。通过UV-Vis、XRD、SEM等技术证实获得粒径~119 nm、具有面心立方结构的球形AgNPs，其对金黄色葡萄球菌(25 mm)和大肠杆菌(33 ...

Biliary tract infections (BTI), often linked to structural abnormalities like bile duct stones, pose significant treatment challenges due to drug-resistant bacteria like Pseudomonas aeruginosa. Phage ...

Researchers at the University of Oklahoma have made a breakthrough discovery that could potentially revolutionize treatments for antibiotic-resistant ...