本研究针对年龄相关性听力损失(ARHL)中耳蜗毛细胞衰老的分子机制，探索了氧化应激诱导的HEI-OC1细胞衰老与NLRP3炎症小体激活 ...

为探究青蒿琥酯（ART）能否通过下调 NLRP3 改善脑小血管病（CSVD）大鼠学习记忆功能，研究人员建立 CSVD 大鼠模型开展研究。结果发现 ART 可改善大鼠认知障碍，下调相关炎症因子，NLRP3 或可成为潜在治疗靶点，为 CSVD 治疗提供新思路。

Host cells activate cell death pathways in response to bacterial manipulation of innate immune signalling, but the molecular mechanisms underlying this interplay are not fully understood. This study ...

A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory ...

A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory ...

Epstein-Barr virus infection induces the upregulation of glycolysis in intestinal macrophages, which subsequently activates Gasdermin D, NLRP3 ... infection activates pyroptosis—a form of ...

WALTHAM, Mass. & MONTREAL--(BUSINESS WIRE)--Ventus Therapeutics, a clinical-stage biopharmaceutical company with two novel small-molecule programs entering Phase 2 development for immunological ...

A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory bowel disease. Researchers ...