本研究针对年龄相关性听力损失(ARHL)中耳蜗毛细胞衰老的分子机制，探索了氧化应激诱导的HEI-OC1细胞衰老与NLRP3炎症小体激活 ...

为探究青蒿琥酯（ART）能否通过下调 NLRP3 改善脑小血管病（CSVD）大鼠学习记忆功能，研究人员建立 CSVD 大鼠模型开展研究。结果发现 ART 可改善大鼠认知障碍，下调相关炎症因子，NLRP3 或可成为潜在治疗靶点，为 CSVD 治疗提供新思路。

A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory bowel disease.

Active caspase 1 causes pyroptosis and is responsible for proteolytic maturation of the inflammatory cytokines interleukin-1β (IL-1β) and IL-18. Pyroptosis is characterized by caspase 1 ...

Epstein-Barr virus infection induces the upregulation of glycolysis in intestinal macrophages, which subsequently activates Gasdermin D, NLRP3 ... infection activates pyroptosis—a form of ...

A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory bowel disease. Researchers discovered that EBV infection triggers macrophage ...

A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory bowel disease. Researchers ...