In normal liver, hepatic stellate cells (HSCs) are nonparenchymal, quiescent cells whose main functions is to store vitamin A and probably to maintain the normal basement membrane-type matrix.

Following liver injury, hepatic stellate cells undergo "activation" which connotes a transition from quiescent vitamin A-rich cells into proliferative, fibrogenic, and contractile myofibroblasts.

In healthy liver, quiescent hepatic stellate cells (HSCs) participate in the homeostasis of extracellular matrix and store vitamin A. After injury, HSCs activate and participate in the wound-healing ...

Under normal physiological conditions, HSCs remain quiescent and are involved ... Regulation in the Fibrogenic Activation of ...