Per reports, it is rare for a biological male Calico Cats to have two chromosomes, as only 1 in every 3,000 has XXY chromosomes. As such, Josie is indeed a very special cat.

That's the case with an extremely rare cat you're about to meet who is not only Calico, but also a boy. Male Calico and Tortoiseshell cats are extremely rare. So rare, in fact, that there is a ...

Humane Society of Central Oregon A rare kitten ended up at an Oregon humane ... throughout her career — and "only seen one other male calico and only a handful of true hermaphrodite animals." ...