Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

The yeast RGG motif-containing RNA binding protein Scd6 and its human ortholog LSM14A regulate the translation of specific ...

Beyond its role in meiosis, recombination is important to somatic cells in eukaryotes because it can be used to help repair broken DNA, even when the break involves both strands of the double helix.

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA ...

The team showed that blocking homologous recombination changed the way the ... radiotherapy depends on the engagement of ...

Both ends can be simply rejoined with little or no further processing (nonhomologous end joining, or NHEJ) or can be repaired using homologous sequences (red DNA; homologous recombination ...

Northwestern Medicine investigators have discovered new molecular mechanisms underlying DNA repair dysregulation ... but they're only used in homologous recombination deficient cancer types ...

The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...