have published a consensus document on the use and monitoring of methotrexate for rheumatic diseases in clinical practice. 1 The 10 recommendations they describe were derived from a review and ...

Only around half of all patients with rheumatoid arthritis (RA) given the disease-modifying antirheumatic drug (DMARD) methotrexate show a good clinical response. Methotrexate is thought to act ...

At the present time, there are no reliable means of predicting, a priori, an individual patient's response to methotrexate. In this review, recent published literature on the pharmacogenetics of ...