The finding, appearing this month in the journal Brain, Behavior, and Immunity, adds insight to an on-off switch for genes called STAT1. This gene regulator plays a pivotal role in the immune ...
成都医学院基础医学院解剖学与组织学胚胎学系的研究人员 Min Liu 等人在《Cell Death and Disease》期刊上发表了题为 “Mcm5 mutation leads to silencing of Stat1-bcl2 which accelerating apoptosis of immature T lymphocytes with DNA damage” ...
The STAT family has six members (STAT1–6), each of which transduces the signal of particular cytokines. For instance, signaling from the interferon (IFN) receptors, interleukin-4 (IL-4 ...
调节性T细胞是维持机体免疫稳态的CD4+ T细胞亚群，也是肿瘤微环境中免疫抑制屏障的主要构成细胞。因此，特异性地调控肿瘤微环境的Treg细胞使其功能与稳定性发生改变，将能够促进肿瘤杀伤反应的发生。
来自暨南大学生命科学与技术学院生命与健康工程研究所肿瘤分子生物学教育部重点实验室等多个单位的研究人员，在《Cell Death and Disease》期刊上发表了题为 “FAM210B activates STAT1/IRF9/IFIT3 axis by ...
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