These biological responses to AZD1480 are associated with concomitant inhibition of phosphorylation of JAK2, STAT3 and MAPK signaling proteins. In addition, there is inhibition of expression of ...

The U.S. Patent and Trademark Office granted a Notice of Allowance for a patent titled "P-ethoxy nucleic acids for STAT3 inhibition," and the New Zealand Intellectual Property Office awarded ...

NT219 in combination with EGFR antibody cetuximab (Erbitux) is currently entering a Phase 2 study for head and neck cancer ...