1B). In all cases, the flap sequence significantly enhanced GFP transduction mediated by the HIV vector. Figure 1: The HIV-1 central DNA flap enhances gene transduction of primary neural cells.

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA sequence loxP, which is its target. This vector allows the creation of ...

Transgenic animals continue to play an essential role in many aspects of zebrafish research, including the development of disease models. The most widely used system for zebrafish transgenesis is the ...

This weeks’ lab will be held in Room B8218 (the Biology PC lab). Raw sequence files will be edited this week, and the edited sequence files will be analyzed next week. Editing (and most of the ...

In this context, we feel that ambiguities in the usage of the terms 'leader sequences' and 'signal peptides' require clarification. The translocation of secretory proteins across intracellular ...

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA sequence loxP, which is its target. This vector allows the creation of ...

Unlike CRISPR, which edits DNA by cutting and altering sequences, VECTOR focuses on repositioning genes without modifying their sequences. This approach could help regulate protein imbalances ...

Adenoviral vectors will transduce a wide range of target cells resulting in high-level gene expression. They are non-integrating vectors so expression in dividing cells is progressively lost. First ...