Scrapie is a prion disease with a long incubation period (2–5 years) that affects the brain and spinal cord of sheep and ...

Figure 4: Immunolabeling for PrP or FDC networks in spleens from BM-reconstituted mice, 10 weeks after challenge with scrapie ... at the terminal stage of the disease. One half of the spleen ...

Chandler, R. L., The Lancet, i, 7191 (1961). Chandler, R. L., The Lancet, i, 7220 (1962). Gordon, W. S., Vet. Rec., 69, 1324 (1957). Hunter, G. D. Paper presented at ...

"Scrapie" is the old Scottish shepherds' name for a disease of their sheep which has been known for several centuries. It is the original example of a group of diseases, known as the ...